extract in ethanol treated rats: in vitro and in vivo studies. et Thonn. Nat.Prod.Res 2006;20(4):323-326. Ekwenye, UN Njoku NU. Taking chanca piedra might decrease how well the body gets rid of lithium. Sharma, P., Parmar, J., Verma, P., and Goyal, P. K. Modulatory influence of Phyllanthus niruri on oxidative stress, antioxidant defense and chemically induced skin tumors. In large amounts, chanca piedra may prevent pregnancy, increase your risk of congenital disabilities, or cause low birth weight. Akinjogunla, OJ Eghafona NO Enabulele IO et al. 2007;45(5):817-826. View abstract. and Thonn. 2004;95(2-3):399-404. View abstract. Failure of New Zealand hepatitis B carriers to respond to Phyllanthus amarus. Bionotes 2002;4(2):40.
Jayaram S, Thyagarajan SP Sumathi S et al. The herb is believed to have health benefits in treating ulcers, urinary tract stones, and various conditions related to the kidneys, liver, and digestive system.. Current Science 2003;84(4):529-533. A clinical study about chanca piedra and its effects on kidney stones showed an increase in potassium excretion when taking chanca piedra. View abstract. One of the earliest studies of chanca piedra found that people who drank a traditionally brewed tea for 1 to 3 months had a significantly reduced rate of kidney stones. & Thonn.) Indian Journal of Natural Products 2006;18-20. Speak with a healthcare professional before taking chanca piedra or any supplement or plant medicine, especially if you are taking any prescription medications. View abstract. New seco- and hydroxy-lignans from Phyllanthus niruri. Chatterjee, M. and Sil, P. C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Murugaiyah, V. and Chan, K. L. Antihyperuricemic lignans from the leaves of Phyllanthus niruri. Some clinico-pathological changes associated with the aqueous extract of the leaves of Phyllanthus amarus in rats. She is focused on preventing and managing chronic diseases through healthy lifestyle changes and is based in the New York area. View abstract. Kidney stones may sound like the punch line of a bad joke, but anyone whos passed one will tell you theyre no laughing matter. It Could Be Your Adrenals, Tame The Flames: 6 Anti-Inflammatory Supplements, Feeling Sluggish and Low on Energy? Alvari A, Rafsanjani MS Ahmed FJ et al. See additional information. View abstract. View abstract. Biol.Trace Elem.Res 2010;133(3):357-363. Most important, chanca piedra doesnt interfere with Lactobacillus acidophilus and other beneficial bacteria in the gut, unlike antibiotics and other medications typically used to treat H. pylori infection. Taking medications that lower blood pressure and chanca piedra may cause your blood pressure to be too low. Some studies suggest higher potassium intake is linked with reduced risk of kidney stone formation. Hepatoprotection by Phyllanthus amarus and Phyllanthus debilis in CCl4-induced liver dysfunction. Duke JA, Vasquez R. Amazonian Ethnobotanical Dictionary. Stop using chanca piedra at least two weeks before a planned surgery. Guha, G., Rajkumar, V., Ashok, Kumar R., and Mathew, L. Aqueous extract of Phyllanthus amarus inhibits chromium(VI)-induced toxicity in MDA-MB-435S cells. Phytotherapy Research 1997;11(8):594-596. 1999;20(4):164-166. However, more research needs to be done. Your lithium dose might need to be changed. It has been found that chanca piedra may help balance out uric acid and prevent gout attacks. Gowrishankar, R., Kumar, M., Menon, V., Divi, S. M., Saravanan, M., Magudapathy, P., Panigrahi, B. K., Nair, K. G., and Venkataramaniah, K. Trace Element Studies on Tinospora cordifolia (Menispermaceae), Ocimum sanctum (Lamiaceae), Moringa oleifera (Moringaceae), and Phyllanthus niruri (Euphorbiaceae) Using PIXE. Environ.Monit.Assess. There is some concern that it might interfere with blood sugar control during and after surgery.
Here is where it gets its name "stonebreaker.". When eating oxalate-rich foods, eat or drink those rich in calcium. Planta Med 1992;58(5):473-474. Notka, F., Meier, G. R., and Wagner, R. Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus. Medicinal plants in the treatment of Helicobacter pylori infections. Clinical study of hepatoprotective drug Phyllanthus amarus. Niu, J. Boca Raton, FL: CRC Press, LLC 1994. Viral hepatitis treated with Phyllanthus amarus and milk thistle (Silybum marianum): a case report [corrected]. View abstract. View abstract. Leelarasamee, A., Trakulsomboon, S., Maunwongyathi, P., Somanabandhu, A., Pidetcha, P., Matrakool, B., Lebnak, T., Ridthimat, W., and Chandanayingyong, D. Failure of Phyllanthus amarus to eradicate hepatitis B surface antigen from symptomless carriers. Rai, V. and Mehrotra, S. Chromium-induced changes in ultramorphology and secondary metabolites of Phyllanthus amarus Schum & Thonn. View abstract. Chanca piedra might decrease blood sugar. Appl.Radiat.Isot. Sundaresan NR, Thirumurugan R Jayakumar S et al. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or doctor. 2008;46(7):514-520. 2007;30(2):382-384. (Euphorbiaceae). Studies on analgesic activity and antipyretic potential of Phyllanthus amarus. B., Antarkar, D. S., Deolalikar, R., and Antani, D. H. A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: failure to eradicate the surface antigen. View abstract. A novel class on non-peptidic endothelin antagonists isolated from the medicinal herb Phyllanthus niruri. Pagare RS, Auti SG Aglave BA et al. View abstract. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1999;12-31. View abstract.
1989;14(2):195-201. Gastroprotective effect of Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. Bhattacharyya R, Bhattacharya S. Development of a potent in vitro source of Phyllanthus amarus roots with pronounced activity against surface antigen of the hepatitis B virus. Phytother.Res 2005;19(11):971-976. Thonn. Pramyothin, P., Ngamtin, C., Poungshompoo, S., and Chaichantipyuth, C. Hepatoprotective activity of Phyllanthus amarus Schum. Ranilla LG et al. Nishiura, J. L., Campos, A. H., Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients. Niruriflavone, a new antioxidant flavone sulfonic acid from Phyllanthus niruri. Huang ZR, Zhong JP, and Zhu GL. (Taung-ze-phyu) on rabbit model. Planta Med 2006;72(14):1262-1267. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1992;6-9. View abstract. 2002 Sep;82(1):19-22. Akinnibosun, FJ Akinnibosun HA Ibeh IN et al. View abstract. Aloe, when taken orally, can decrease potassium levels in the body. 1990;32(4):212-218. Create a personalized feed and bookmark your favorites. Warning letter: Herbs America, Inc, Boim MA, Heilberg IP, Schor N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. A., Rehder, V. L., and Calixto, J. African Journal of Biotechnology 2010;248-259. Vitamin D Deficiency: How Much Vitamin D Is Enough? Food and Drug Administration. Speak with a healthcare professional about taking chanca piedra if you are using diuretics or have any concerns about your potassium levels. Chemosphere 2005;61(11):1644-1650. 2006;29(7):1310-1313. Devi, V., Shanbhag, T. V., Bairy, K. L., Rao, N., and Shenoy, S. Effect of Phyllanthus niruri on wound healing in rats. Amli, Arranca-Pedras, Bhonya, Bhoomi Amalaki, Bhui-Amla, Bhumi Amla, Bhuianvalah, Bhuimy Amali, Bhuin Amla, Bhumy Amalaki, Bhumyamalaki, Brise Pierre, Cane Peas Senna, Cane Senna, Carry-Me-Seed, Casse-Pierre, Chancapiedra, Chanca-Piedra Blanca, Chance Pierre, Child Pick-a-Back, Creole Senna, Daun Marisan, Derriere-Dos, Des Dos, Deye Do, Dukong Anak, Elrageig, Elrigeg, Erva-Pombinha, Evatbimi, Feuilles la Fièvre, Gale-Wind Grass, Graine En Bas Fièvre, Graine-En-Bas-Feuille, Hurricane Weed, Jar-Amla, Jar Amla, Kizha Nelli, Malva-Pedra, Mapatan, Memeniran, Meniran, Niruri, Nymphanthus niruri, Para-Parai Mi, Paraparai Mi, Pei, Phyllanto, Phyllanthus amarus, Phyllanthus carolinianus, Phyllanthus fraternus, Phyllanthus kirganella, Phyllanthus lathyroides, Phyllanthus lonphali, Phyllanthus niruri, Phyllanthus sellowianus, Pierre de Chanca, Pitirishi, Pombinha, Punarnava, Quebra Pedra, Quebrapedra, Quinina Criolla, Quinine Creole, Quinine Weed, Rami Buah, Sacha Foster, Sasha Foster, Seed on the Leaf, Semence dans la Feuille, Shka-Nin-Du, Shatter Stone, Stone Breaker, Stone-Breaker, Stonebreaker, Tamalaka, Turi Hutan, Viernes Santo, Ya-Taibai, Yaa Tai Bai, Yah-Tai-Bai, Yerba de San Pablo. Study authors said that the chanca piedra might be effective against hepatitis B by slowing the replication (growth) of the hepatitis B virus. What Are the Side Effects of Chanca Piedra? View abstract. Indian J Exp Biol 1995; 33:861-4. Drink plenty of water (and other fluids). Hamdard Medicus 2008;198-201. 2. Immunol.Invest 2010;39(3):245-267. Indian Journal of Pharmaceutical Sciences 2007;33-36. In a 2010 study, chanca piedra "interfered with different stages of [kidney] stone formation." www.ars-grin.gov/duke (Accessed 3 November 1999). Effect of Phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. For breastfeeding women, its best to avoid using the herb due to a lack of safety information. J Nat.Prod. Eur J Clin Invest 1997;27(11):908-915. Srividya N, Periwal S. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. The right dose of any supplement depends on many factors, including age, body weight, and overall health. Harikumar, K. B., Kuttan, G., and Kuttan, R. Inhibition of viral carcinogenesis by Phyllanthus amarus. Observation on the effect of fujian's Phyllanthus amarus in treatment of HBV infection. 2005 - 2019 WebMD LLC. Xin-Hua, W., Chang-Qing, L., Xing-Bo, G., and Lin-Chun, F. A comparative study of Phyllanthus amarus compound and interferon in the treatment of chronic viral hepatitis B. Southeast Asian J Trop.Med Public Health 2001;32(1):140-142. Phytochemistry 1993;33(2):487-491. Enders D, Milovanovic' M. Asymmetric synthesis of (+)-hinokinin, (+)-dihydrocubebin and cubebin dimethyl ether, a new lignan from Phyllanthus niruri. Try to get more of your daily protein from vegetable sources.
It is thought that chanca piedra contains chemicals that might relieve spasms and fever, increase urine, and have activity against bacteria and viruses. Kumar, K. B. and Kuttan, R. Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice. Hepatitis B is a serious liver disease. View abstract. Thyagarajan, S. P., Subramanian, S., Thirunalasundari, T., Venkateswaran, P. S., and Blumberg, B. S. Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus. In vitro antiplasmodial activity of callus culture extracts and fractions from fresh apical stems of Phyllanthus niruri L. (Euphorbiaceae): part 2. Blumberg, B. S., Millman, I., Venkateswaran, P. S., and Thyagarajan, S. P. Hepatitis B virus and primary hepatocellular carcinoma: treatment of HBV carriers with Phyllanthus amarus. Sirajudeen KN, Sulaiman SA Madhavan M et al. Cimanga, R. K., Tona, L., Luyindula, N., Mesia, K., Lusakibanza, M., Musuamba, C. T., Apers, S., De, Bruyne T., Van, Miert S., Hermans, N., Totte, J., Pieters, L., and Vlietinck, A. J. on aflatoxin B 1-induced liver damage in mice. Phytother.Res 2006;20(7):595-601. 2010;36(6):657-64. doi:10.1590/s1677-55382010000600002, Lee NY, Khoo WK, Adnan MA, Mahalingam TP, Fernandez AR, Jeevaratnam K. The pharmacological potential of Phyllanthus niruri. Excessive excretion of potassium can decrease potassium to unsafe levels, causing an electrolyte imbalance. To prevent uric acid kidney stones, reduce the amount of meat, eggs, fish, and poultry you eat. Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Radioprotective properties of polyphenols from Phyllanthus amarus Linn. 2002;40(8):905-909. Always check with your health care provider before taking herbs or supplements, and then see how this traditional herb can help you: Chanca piedra helps decrease urinary oxalate and uric acid levels, reducing the risk of kidney stones. Dhalwal, K., Biradar, Y. S., and Rajani, M. High-performance thin-layer chromatography densitometric method for simultaneous quantitation of phyllanthin, hypophyllanthin, gallic acid, and ellagic acid in Phyllanthus amarus. on the hematological parameters of rats. Amariinic acid and related ellagitannins from Phyllanthus amarus. View abstract. Moshi, M. J., Lutale, J. J., Rimoy, G. H., Abbas, Z. G., Josiah, R. M., and Swai, A. Avoid foods high in oxalates, compounds that occur naturally in many foods and are the basis for many kidney stones. Bhattacharjee, R. and Sil, P. C. Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. Preventive effect of Phyllanthus amarus on prostatic hyperplasia. Acta Pol.Pharm. View abstract. Peace Health. The comparative effects of methanol extract of Phyllanthus amarus leaves and Vitamin E on the sperm parameters of male guinea pigs. Journal of Ethnopharmacology 2007;503-509. View abstract.
Houghton PJ, Woldemariam TZ O'Shea S et al. The study also found that chanca piedra didn't inhibit the growth of good bacteria in the gut (such as Lactobacillus acidophilus). Faremi, T. Y., Suru, S. M., Fafunso, M. A., and Obioha, U. E. Hepatoprotective potentials of Phyllanthusamarus against ethanol-induced oxidative stress in rats. Than NN, Fotso S Poeggeler B et al.
Paris: Lavoisier Publishing, 1995. No clinical study validates these doses. Jayaram, S. and Thyagarajan, S. P. Inhibition of HBsAg secretion from Alexander cell line by Phyllanthus amarus. Wien Med Wochenschr. Failure of New Zealand hepatitis B carriers to respond to Phyllanthus amarus.
View abstract. It remains uncertain if these side effects directly resulted from using chanca piedra. The effects of chromatographic fractions of Phyllanthus amarus Schum. Effect of Phyllanthus niruri.
Harikumar, K. B. and Kuttan, R. An extract of Phyllanthus amarus protects mouse chromosomes and intestine from radiation induced damages. Amir M, Kumar S Singh SK. 3. J Hepatol. View abstract. Phytochemistry 1995;39(1):217-224. J Radiat.Res 2009;50(4):303-309. Chezhiyan N, Saraswathy S Vasumathi R. Studies on organic manures, biofertilizers and plant density on growth, yield and alkaloid content of bhumyamalaki (Phyllanthus amarus Schum.
Jayaram S, Thyagarajan SP Sumathi S et al. The herb is believed to have health benefits in treating ulcers, urinary tract stones, and various conditions related to the kidneys, liver, and digestive system.. Current Science 2003;84(4):529-533. A clinical study about chanca piedra and its effects on kidney stones showed an increase in potassium excretion when taking chanca piedra. View abstract. One of the earliest studies of chanca piedra found that people who drank a traditionally brewed tea for 1 to 3 months had a significantly reduced rate of kidney stones. & Thonn.) Indian Journal of Natural Products 2006;18-20. Speak with a healthcare professional before taking chanca piedra or any supplement or plant medicine, especially if you are taking any prescription medications. View abstract. New seco- and hydroxy-lignans from Phyllanthus niruri. Chatterjee, M. and Sil, P. C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Murugaiyah, V. and Chan, K. L. Antihyperuricemic lignans from the leaves of Phyllanthus niruri. Some clinico-pathological changes associated with the aqueous extract of the leaves of Phyllanthus amarus in rats. She is focused on preventing and managing chronic diseases through healthy lifestyle changes and is based in the New York area. View abstract. Kidney stones may sound like the punch line of a bad joke, but anyone whos passed one will tell you theyre no laughing matter. It Could Be Your Adrenals, Tame The Flames: 6 Anti-Inflammatory Supplements, Feeling Sluggish and Low on Energy? Alvari A, Rafsanjani MS Ahmed FJ et al. See additional information. View abstract. View abstract. Biol.Trace Elem.Res 2010;133(3):357-363. Most important, chanca piedra doesnt interfere with Lactobacillus acidophilus and other beneficial bacteria in the gut, unlike antibiotics and other medications typically used to treat H. pylori infection. Taking medications that lower blood pressure and chanca piedra may cause your blood pressure to be too low. Some studies suggest higher potassium intake is linked with reduced risk of kidney stone formation. Hepatoprotection by Phyllanthus amarus and Phyllanthus debilis in CCl4-induced liver dysfunction. Duke JA, Vasquez R. Amazonian Ethnobotanical Dictionary. Stop using chanca piedra at least two weeks before a planned surgery. Guha, G., Rajkumar, V., Ashok, Kumar R., and Mathew, L. Aqueous extract of Phyllanthus amarus inhibits chromium(VI)-induced toxicity in MDA-MB-435S cells. Phytotherapy Research 1997;11(8):594-596. 1999;20(4):164-166. However, more research needs to be done. Your lithium dose might need to be changed. It has been found that chanca piedra may help balance out uric acid and prevent gout attacks. Gowrishankar, R., Kumar, M., Menon, V., Divi, S. M., Saravanan, M., Magudapathy, P., Panigrahi, B. K., Nair, K. G., and Venkataramaniah, K. Trace Element Studies on Tinospora cordifolia (Menispermaceae), Ocimum sanctum (Lamiaceae), Moringa oleifera (Moringaceae), and Phyllanthus niruri (Euphorbiaceae) Using PIXE. Environ.Monit.Assess. There is some concern that it might interfere with blood sugar control during and after surgery.
Here is where it gets its name "stonebreaker.". When eating oxalate-rich foods, eat or drink those rich in calcium. Planta Med 1992;58(5):473-474. Notka, F., Meier, G. R., and Wagner, R. Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus. Medicinal plants in the treatment of Helicobacter pylori infections. Clinical study of hepatoprotective drug Phyllanthus amarus. Niu, J. Boca Raton, FL: CRC Press, LLC 1994. Viral hepatitis treated with Phyllanthus amarus and milk thistle (Silybum marianum): a case report [corrected]. View abstract. View abstract. Leelarasamee, A., Trakulsomboon, S., Maunwongyathi, P., Somanabandhu, A., Pidetcha, P., Matrakool, B., Lebnak, T., Ridthimat, W., and Chandanayingyong, D. Failure of Phyllanthus amarus to eradicate hepatitis B surface antigen from symptomless carriers. Rai, V. and Mehrotra, S. Chromium-induced changes in ultramorphology and secondary metabolites of Phyllanthus amarus Schum & Thonn. View abstract. Chanca piedra might decrease blood sugar. Appl.Radiat.Isot. Sundaresan NR, Thirumurugan R Jayakumar S et al. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or doctor. 2008;46(7):514-520. 2007;30(2):382-384. (Euphorbiaceae). Studies on analgesic activity and antipyretic potential of Phyllanthus amarus. B., Antarkar, D. S., Deolalikar, R., and Antani, D. H. A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: failure to eradicate the surface antigen. View abstract. A novel class on non-peptidic endothelin antagonists isolated from the medicinal herb Phyllanthus niruri. Pagare RS, Auti SG Aglave BA et al. View abstract. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1999;12-31. View abstract.
1989;14(2):195-201. Gastroprotective effect of Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. Bhattacharyya R, Bhattacharya S. Development of a potent in vitro source of Phyllanthus amarus roots with pronounced activity against surface antigen of the hepatitis B virus. Phytother.Res 2005;19(11):971-976. Thonn. Pramyothin, P., Ngamtin, C., Poungshompoo, S., and Chaichantipyuth, C. Hepatoprotective activity of Phyllanthus amarus Schum. Ranilla LG et al. Nishiura, J. L., Campos, A. H., Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients. Niruriflavone, a new antioxidant flavone sulfonic acid from Phyllanthus niruri. Huang ZR, Zhong JP, and Zhu GL. (Taung-ze-phyu) on rabbit model. Planta Med 2006;72(14):1262-1267. Chinese Journal of Integrated Traditional & Western Medicine on Liver Diseases 1992;6-9. View abstract. 2002 Sep;82(1):19-22. Akinnibosun, FJ Akinnibosun HA Ibeh IN et al. View abstract. Aloe, when taken orally, can decrease potassium levels in the body. 1990;32(4):212-218. Create a personalized feed and bookmark your favorites. Warning letter: Herbs America, Inc, Boim MA, Heilberg IP, Schor N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. A., Rehder, V. L., and Calixto, J. African Journal of Biotechnology 2010;248-259. Vitamin D Deficiency: How Much Vitamin D Is Enough? Food and Drug Administration. Speak with a healthcare professional about taking chanca piedra if you are using diuretics or have any concerns about your potassium levels. Chemosphere 2005;61(11):1644-1650. 2006;29(7):1310-1313. Devi, V., Shanbhag, T. V., Bairy, K. L., Rao, N., and Shenoy, S. Effect of Phyllanthus niruri on wound healing in rats. Amli, Arranca-Pedras, Bhonya, Bhoomi Amalaki, Bhui-Amla, Bhumi Amla, Bhuianvalah, Bhuimy Amali, Bhuin Amla, Bhumy Amalaki, Bhumyamalaki, Brise Pierre, Cane Peas Senna, Cane Senna, Carry-Me-Seed, Casse-Pierre, Chancapiedra, Chanca-Piedra Blanca, Chance Pierre, Child Pick-a-Back, Creole Senna, Daun Marisan, Derriere-Dos, Des Dos, Deye Do, Dukong Anak, Elrageig, Elrigeg, Erva-Pombinha, Evatbimi, Feuilles la Fièvre, Gale-Wind Grass, Graine En Bas Fièvre, Graine-En-Bas-Feuille, Hurricane Weed, Jar-Amla, Jar Amla, Kizha Nelli, Malva-Pedra, Mapatan, Memeniran, Meniran, Niruri, Nymphanthus niruri, Para-Parai Mi, Paraparai Mi, Pei, Phyllanto, Phyllanthus amarus, Phyllanthus carolinianus, Phyllanthus fraternus, Phyllanthus kirganella, Phyllanthus lathyroides, Phyllanthus lonphali, Phyllanthus niruri, Phyllanthus sellowianus, Pierre de Chanca, Pitirishi, Pombinha, Punarnava, Quebra Pedra, Quebrapedra, Quinina Criolla, Quinine Creole, Quinine Weed, Rami Buah, Sacha Foster, Sasha Foster, Seed on the Leaf, Semence dans la Feuille, Shka-Nin-Du, Shatter Stone, Stone Breaker, Stone-Breaker, Stonebreaker, Tamalaka, Turi Hutan, Viernes Santo, Ya-Taibai, Yaa Tai Bai, Yah-Tai-Bai, Yerba de San Pablo. Study authors said that the chanca piedra might be effective against hepatitis B by slowing the replication (growth) of the hepatitis B virus. What Are the Side Effects of Chanca Piedra? View abstract. Indian J Exp Biol 1995; 33:861-4. Drink plenty of water (and other fluids). Hamdard Medicus 2008;198-201. 2. Immunol.Invest 2010;39(3):245-267. Indian Journal of Pharmaceutical Sciences 2007;33-36. In a 2010 study, chanca piedra "interfered with different stages of [kidney] stone formation." www.ars-grin.gov/duke (Accessed 3 November 1999). Effect of Phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. For breastfeeding women, its best to avoid using the herb due to a lack of safety information. J Nat.Prod. Eur J Clin Invest 1997;27(11):908-915. Srividya N, Periwal S. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. The right dose of any supplement depends on many factors, including age, body weight, and overall health. Harikumar, K. B., Kuttan, G., and Kuttan, R. Inhibition of viral carcinogenesis by Phyllanthus amarus. Observation on the effect of fujian's Phyllanthus amarus in treatment of HBV infection. 2005 - 2019 WebMD LLC. Xin-Hua, W., Chang-Qing, L., Xing-Bo, G., and Lin-Chun, F. A comparative study of Phyllanthus amarus compound and interferon in the treatment of chronic viral hepatitis B. Southeast Asian J Trop.Med Public Health 2001;32(1):140-142. Phytochemistry 1993;33(2):487-491. Enders D, Milovanovic' M. Asymmetric synthesis of (+)-hinokinin, (+)-dihydrocubebin and cubebin dimethyl ether, a new lignan from Phyllanthus niruri. Try to get more of your daily protein from vegetable sources.
It is thought that chanca piedra contains chemicals that might relieve spasms and fever, increase urine, and have activity against bacteria and viruses. Kumar, K. B. and Kuttan, R. Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice. Hepatitis B is a serious liver disease. View abstract. Thyagarajan, S. P., Subramanian, S., Thirunalasundari, T., Venkateswaran, P. S., and Blumberg, B. S. Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus. In vitro antiplasmodial activity of callus culture extracts and fractions from fresh apical stems of Phyllanthus niruri L. (Euphorbiaceae): part 2. Blumberg, B. S., Millman, I., Venkateswaran, P. S., and Thyagarajan, S. P. Hepatitis B virus and primary hepatocellular carcinoma: treatment of HBV carriers with Phyllanthus amarus. Sirajudeen KN, Sulaiman SA Madhavan M et al. Cimanga, R. K., Tona, L., Luyindula, N., Mesia, K., Lusakibanza, M., Musuamba, C. T., Apers, S., De, Bruyne T., Van, Miert S., Hermans, N., Totte, J., Pieters, L., and Vlietinck, A. J. on aflatoxin B 1-induced liver damage in mice. Phytother.Res 2006;20(7):595-601. 2010;36(6):657-64. doi:10.1590/s1677-55382010000600002, Lee NY, Khoo WK, Adnan MA, Mahalingam TP, Fernandez AR, Jeevaratnam K. The pharmacological potential of Phyllanthus niruri. Excessive excretion of potassium can decrease potassium to unsafe levels, causing an electrolyte imbalance. To prevent uric acid kidney stones, reduce the amount of meat, eggs, fish, and poultry you eat. Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Radioprotective properties of polyphenols from Phyllanthus amarus Linn. 2002;40(8):905-909. Always check with your health care provider before taking herbs or supplements, and then see how this traditional herb can help you: Chanca piedra helps decrease urinary oxalate and uric acid levels, reducing the risk of kidney stones. Dhalwal, K., Biradar, Y. S., and Rajani, M. High-performance thin-layer chromatography densitometric method for simultaneous quantitation of phyllanthin, hypophyllanthin, gallic acid, and ellagic acid in Phyllanthus amarus. on the hematological parameters of rats. Amariinic acid and related ellagitannins from Phyllanthus amarus. View abstract. Moshi, M. J., Lutale, J. J., Rimoy, G. H., Abbas, Z. G., Josiah, R. M., and Swai, A. Avoid foods high in oxalates, compounds that occur naturally in many foods and are the basis for many kidney stones. Bhattacharjee, R. and Sil, P. C. Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. Preventive effect of Phyllanthus amarus on prostatic hyperplasia. Acta Pol.Pharm. View abstract. Peace Health. The comparative effects of methanol extract of Phyllanthus amarus leaves and Vitamin E on the sperm parameters of male guinea pigs. Journal of Ethnopharmacology 2007;503-509. View abstract.
Houghton PJ, Woldemariam TZ O'Shea S et al. The study also found that chanca piedra didn't inhibit the growth of good bacteria in the gut (such as Lactobacillus acidophilus). Faremi, T. Y., Suru, S. M., Fafunso, M. A., and Obioha, U. E. Hepatoprotective potentials of Phyllanthusamarus against ethanol-induced oxidative stress in rats. Than NN, Fotso S Poeggeler B et al.
Paris: Lavoisier Publishing, 1995. No clinical study validates these doses. Jayaram, S. and Thyagarajan, S. P. Inhibition of HBsAg secretion from Alexander cell line by Phyllanthus amarus. Wien Med Wochenschr. Failure of New Zealand hepatitis B carriers to respond to Phyllanthus amarus.
View abstract. It remains uncertain if these side effects directly resulted from using chanca piedra. The effects of chromatographic fractions of Phyllanthus amarus Schum. Effect of Phyllanthus niruri.
Harikumar, K. B. and Kuttan, R. An extract of Phyllanthus amarus protects mouse chromosomes and intestine from radiation induced damages. Amir M, Kumar S Singh SK. 3. J Hepatol. View abstract. Phytochemistry 1995;39(1):217-224. J Radiat.Res 2009;50(4):303-309. Chezhiyan N, Saraswathy S Vasumathi R. Studies on organic manures, biofertilizers and plant density on growth, yield and alkaloid content of bhumyamalaki (Phyllanthus amarus Schum.